What is Sildenafil Citrate?
Sildenafil is a phosphodiesterase type 5 inhibitor and an active substance of Viagra as well. It increases blood flow and enhances relaxing effect of nitrogen oxide on unstriated muscles of the cavernous body. Sildenafil comes into force exclusively in case of sexual arousal which must result in a steady natural erection. The phosphodiesterase type 5 inhibitor produced by organism after emission of seminal fluid brings penis back to its usual state. Sildenafil inhibits the process of its production prolonging erection by that. Induced by it, sexual intercourse becomes not only more qualitative, but also long-lasting. The first signs of sildenafil’s action appear approximately in one hour after its intake. The effect lasts around 3-4 hours.
What Do We Know about Generics?
Generic sildenafil means medications produced according to the same chemical composition as the original, Viagra, but by other pharmaceutical manufacturers. In order to make sure that the quality of generics is not worse than the originals’ one, it is important to pay much attention to companies manufacturing them. A big advantage of analogues is their moderate price along with the characteristics similar to the originals’ ones. Companies producing generics work with the ready formula and do not spend money on elaboration of production process and advertising. Therefore, their prime cost is several-fold lower. Another advantage of generics is diversity of their dosages and forms of presentation. Original medications are issued only in form of tablets for peroral absorption. Viagra generics are distinguished by a great variety of dosages and presentation forms. Each man is able to choose the most convenient form individually.
Generic Sildenafil Applications
This medication is indicative for erectile dysfunction of any origin: physiological, psychological or mixed, and of any severity of disorder. Moreover, generic sildenafil may be used for improvement of sexual intercourse quality and experiencing of new exciting feelings.
Generic Sildenafil Contraindications
Sildenafil and remedies containing it are counter-indicative if a man suffers from the following diseases:
- pigmented retinitis;
- sickle-cell anemia;
- deformation of penis;
- stomach ulcer;
- other diseases accompanied by bleeding;
- erythroid myeloma;
- severe cardiovascular diseases limiting any physical activities;
- serious diseases of nephros and hepar;
Generic sildenafil is not for women and children up to age 18.
It is prohibited to take the remedy along with nitrogen oxide, nitrates, other medications for sexual dysfunction and some anti-viral medicines.
Before using Generic sildenafil you should consult your attending doctor in order to determine counter-indications and optimal dosage.
Generic Sildenafil Side-Effects
In some cases (it is mostly relevant for overdoses) after the intake of the remedy the side-effects may occur, e.g. vertigo, blushing of upper body part, indigestion, rhinedema, changes in vision. These cases require immediate medical attendance.
Generic Sildenafil Route of Administration
Very often young men take 100 and 50 mg of this drug. This enables to achieve the maximally possible effect. Those who are going to try this medication for the first time should take 25mg. The dosage is indicative for elderly men and for those who suffer from chronic diseases. In severe cases of erectile dysfunction, the optimal dosage is 100mg. While meeting the requirements of Generic sildenafil usage, you may acquire a lot of unforgettable feelings during the sexual intercourse.
Product Forms of Generic Sildenafil Citrate
There is a variety of issuance forms of this medication. It is produced:
- in form of tablets (Viprogra-100, Kamagra, etc.);
- in form of chewable and sucking tablets (e.g. Delgra Soft 100mg). They do not require to be washed down with water. In some cases, it is a substantial advantage. Besides, their action begins in 10-15 minutes, since the drugs are absorbed right into capillaries blood located in mouth cavity;
- in form of gel (e.g. Kamini Oraj Jelly). Gel may be taken without water or diluted in juice or another non-alcohol drink. It has pleasing savors. The gel is absorbed in blood in small capillaries causing the fast effect (10-15 minutes);
- in form of capsules with liquid contents (for example, Delgra-100 Sildenafil Softgel Capsules, also known as Viagra Super Active). Liquid is absorbed faster (the effect comes in 20-30 minutes);
Generic Sildenafil in Tablets
Tablets of Generic sildenafil are represented in maximum permissible for single-use dosage of 100mg. They are covered with coating. In the majority of cases the assigned dose makes 50mg (divide the tablet into two). If you suffer from either penis deformation, or severe disease of nephros and hepar, or cardiovascular disease, the intake of tablet must be reduced to the dosage of 25mg. This form of Generic sildenafil will provide perfect results. You may count on excellent erection, continuous sexual intercourse, exciting feelings and long-lasting orgasm. Sensations and orgasm become enhanced because the drug causes sensitivity of genitals. The medication is to be taken once per day. Generic sildenafil at Smart Canadian Pharmacy is effective only in case of sexual excitement, thus uncaused erection doesn’t occur or is considered as a rare complication.
Generic Sildenafil in Capsules
Capsules of Generic sildenafil contain the dosage of 100mg. This remedy is issued in from of gelatin capsules packed in blisters. While penetrating into blood, sildenafil citrate inhibits the operation of phosphodiesterase type 5 inhibitor which is concentrated in penis tissues. As a result, a concentration of cyclic guanosine monophosphate in the tissues of cavernous bodies relaxing their cells and increasing blood supply to them starts growing. This process causes erection. This is exactly nitrogen oxide which launches the chain of all abovementioned chemical reactions. Liberation of nitrogen oxide by nerve terminals starts only in case of sexual arousal and is impossible without it.
Generic Sildenafil Gel
One package of Generic sildenafil gel contains 100mg of sildenafil with pleasing savour. This is a maximal daily dose of medication. In case this quantity of active substance is too big for you, take only a half of the bag. As a result of sildenafil’s action the unstriated muscles of penis relax, vessels enlarge and blood circulation activates. Sexual stimulation and arousal cause the filling of penis with blood and occurrence of steady erection. If you suffer from either penis deformation, or severe disease of nephros and hepar, or cardiovascular disease, the intake of gel must be reduced to the dosage of 25mg (to ¼ of bag). Generic sildenafil gel is dedicated for erectile dysfunction treatment for any etiology and for men at any age.
Generic Sildenafil Jellies (Chewable and Sucking Pills)
These forms of Generic sildenafil are dedicated for sucking and chewing. Their main advantage consists in shirt interim between the intake and onset of action. It is recommended to use jellies if you do not tolerate treatment with pills. Moreover, sucking and chewing pills with pleasing savour do not resemble therapy. Their intake will cause only pleasure. Generic sildenafil jellies should be taken in dosage of 100mg. If you haven’t taken any medications for erectile dysfunction, it is better to start with ½ pill (50mg). Maximal daily dose is 1 pill.
Generic Sildenafil: Major Comparison of Tablets, Capsules, Gel and Jellies
The onset time of various product forms is different; therefore, they should be taken in such a way that the required effect occurred timely. Thus, the tablets should be taken one hour before sexual intercourse, gel and jellies – 10-15 minutes, capsules – 20-30 minutes before this. Anyway, it is necessary to remember that it is prohibited to reduce the interim between intakes. It must be not less than 24 hours.
Let us consider this topic in greater detail:
- For tablets, it takes 40-60 minutes to be absorbed into blood. Sildenafil enhances blood supply to penis and causes erection. After the ending of sexual intercourse, a penis returns its relaxed condition, the only difference being that the recovery period is a bit shorter than while the common sexual intercourse.
- Generic sildenafil capsules should be taken under fasting conditions around 30 minutes prior to the sexual intercourse. The intake after food interrupts absorption of active substance and its effect may either not develop or become very weak. Do not combine sildenafil with alcoholic drinks casing dangerous arterial blood pressure drop and do not wash it off with grapefruit juice which may change the work of liver enzymes and resulting in overdose of sildenafil citrate and subsequent enhanced side-effects. Capsules start coming into action in 15 minutes.
- Gel may be taken right from bags where the medication is packed or diluted it in non-alcohol beverage and drunken 10-15 minutes before sexual intercourse. You must not combine the intake of Generic sildenafil gel with alcohol. It is possible to have a non-substantial meal before its intake. In accordance with the existing dosage a bag may be divided into portions. The interim between intakes should be not less than 24 hours.
- Jellies should be taken 30-45 minutes before the expected sexual intercourse with a lot of water. These product forms come to action in 15-20 minutes. Hearty meal may slow down occurrence of effect considerably. After the intake coitus is possible within 4-5 hours.
- The effect of tablets lasts 4-5 hours. Sexual intercourse becomes not only more qualitative, but also long-lasting.
- Capsules keep their effect for 4 hours. Their effect is headlong thanks to the fact that the active substance of capsules is in jelly-like condition. It is placed into a gelatin capsule which after the intake is absorbed much faster than usual tablets.
- The huge advantage of gel is its fast onset time and long-lasting effect duration. It takes only ten minutes from the intake to occurrence of action. Such a speed is explained by consistency of jelly which is absorbed into tiny capillaries right in mouth cavity. The substance is less affected by digestive juice and food. Therefore, substantial food doesn’t reduce its action. The effect lasts up to 6 hours. Those who dislike tablets will be pleased to try a gel form. It has a savory flavor and looks more like a dessert than a medicine.
- Jellies continue their action within 3-4 hours. In comparison with other medication forms of Generic sildenafil, this is the least effect duration. But it is quite enough to experience a wonderful sexual intercourse.
- Nowadays jellies are the most popular product form of Generic sildenafil among others. Its high efficiency along with reasonable price makes this analogue become in requisition. Jellies’ action is very fast; therefore, it may be taken even by people suffering from peptic ulcer.
- The most long-running form of Generic sildenafil is gel lasting 6 hours. Its pleasant fruit flavor and capability to get absorbed in mouth cavity within 10 minutes makes it a perfect remedy for those who cannot or doesn’t like to take tablets.
- Capsules also have a perfect absorption period (much faster than the one of tablets) and duration of effect. Although for those who need to divide a capsule into two, it is rather problematic.
- The most usual form of Generic sildenafil is tablets. They will be useful for those who do not want to experiment and choose the most well-tried variants.